Best Ergonomic Gaming Mouse 2020 – High DPI Vertical Gaming Mice

Best overall gaming mouse

Logitech MX Vertical

Our Score: 5 / 5

Logitech MX Vertical
  • Best in class DPI (4000)
  • Can be used either wired or wireless
  • Logitech Flow for use across three computers at the same time
  • Premium ergonomic design
  • High-precision laser sensor

Designed for gaming

ZLOT Vertical Gaming Mouse

Our Score: 4.75 / 5

ZLOT Vertical Gaming Mouse
  • Adjustable DPI which caps out at 3200
  • 6 buttons which can be mapped to in-game functions
  • Affordable dedicated gaming mouse
  • Ergonomic design minimises wrist pain while gaming

Best lightweight mouse

Anker 2.4G Vertical Mouse

Our Score: 4.75 / 5

Anker 2.4G Vertical Mouse
  • Lightweight design makes it easy to move around
  • Battery saving kicks in after 8 minutes of inactivity
  • Affordable option
  • Adjustable DPI and solid tracking

Table of Contents

Quick Guide
We’ve done extensive research on ergonomics and the types of computer mouse which we have compiled into guides to help you find the best product. Here is a small navigation menu so you can jump between these ergonomic mouse articles.

While RSIs and other mouse-related injuries often come about as a result of countless hours spent working, they can also show up from gaming.

If you’re a hardcore gamer, you could definitely stand to gain a lot from using an ergonomic gaming mouse. Not only will it help keep your arm and wrist in a natural position as you play, but it can even improve your performance on match day. Just because ergonomic mice are designed to be more comfortable, it doesn’t mean that they aren’t suitable for gaming. In fact, there are a number of excellent options that can provide the high precision sensor and DPI you need to excel at whatever game you’re currently enjoying.

Our favorites are the Logitech MX Vertical, and the ZLOT vertical gaming mouse. The MX Vertical is one of the best vertical mice available, and it ticks all the boxes for casual or hardcore gaming.

It has a best in class laser sensor with a high DPI for registering the most precise movements.

Then, for those who take gaming seriously, there’s Logitech Flow.

This will let you move your mouse across several computers, which is especially great if you’re a streamer. The ZLOT gaming mouse is a more affordable option, and one that is dedicated to gaming. It features conveniently placed buttons and an adjustable DPI that goes as high as 3200. This one is a solid option if you’re strapped for cash but crave a comfortable, yet quality gaming mouse.

Is a vertical mouse good for gaming?

A vertical mouse can be used for gaming just as well as a regular, horizontal mouse.

The only potential problem is that it will take some time to get used to using a vertical mouse, so your gaming performance will suffer in the beginning. In the long run though, if you practice using it a lot until you are comfortable with it, you can have a very enjoyable experience gaming with it.

You can find vertical mice with high precision sensors, solid DPI, and all the buttons you need for whatever games it is you like to play.

Side-by-side product comparison - specifications & features

ImageModelOverall RatingSize (Inches)Weight (Ounces)DPISensorButtonsConnection Type
Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, GraphiteLogitech MX Vertical53.09x3.11x4.724.75400- 4000Laser4Wireless or Wired
ZLOT Vertical Gaming Mouse,Wired RGB Ergonomic USB Joystick Programmable Laser Gaming Mice,6+1 Design,11 Buttons,1000 Hz Max Polling Rate,10000 Max DPI,2019 Upgraded Version for Computer Gamers,BlackZLOT Vertical Gaming Mouse4.754.33x2.83x2.957.21200-3200Optical6Wired
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - BlackAnker 2.4G4.753.98x3.23x3.153.36800-1600Optical5Wireless
J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Endurance, Removable Palm Rest & Thumb Buttons [V628]J-Tech Digital V6284.753.90x3.74x5.8311.3800-1600Optical4Wired
Wired Ergonomic Mouse, AUTLEY Vertical Mouse USB Wired Mouse for Laptop Desktop Computer Mac, 1000/1600/2400/3200 DPI, Better for Large Hands, BlackAUTLEY Vertical Mouse4.754.84x3.54x2.877.21000-3200Optical5Wired

Our top ergonomic gaming mouse picks

#1 Best overall gaming mouse

Logitech MX Vertical

Logitech MX Vertical

Our Score: 5 / 5

Editor's opinion:

The MX Vertical from Logitech boasts best in class DPI (up to 4000) which enables a seamless gaming experience, whether you want to play casually or with higher stakes.

This mouse has a nice, premium feel to it. With a precise scroll wheel, and ergonomic design, you can have the ultimate gaming experience without putting your wrists at risk.

Access to Logitech Flow means with this mouse you can navigate across up to three computers, in case you crave a more complete experience.

Pros

  • Best in class DPI (4000)
  • Can be used either wired or wireless
  • Logitech Flow for use across three computers at the same time
  • Premium ergonomic design
  • High-precision laser sensor

Cons

  • Buttons require some force to press

Wired or wireless, it’s your choice how you use this mouse for gaming. If you are wondering which version is best, then you can settle the debate for yourself with the MX Vertical. This versatility allows you to game in the way that best suits your playstyle, rather than settling for one version and then finding out it’s not right for you.

The best parts about this ergonomic mouse for gaming are undoubtedly the high DPI of 4000 and the high-precision laser sensor. Being equipped with a laser sensor, the MX Vertical has an edge on many of its ergonomic mice competitions, since it has far greater DPI. This makes this one of the best, and only, mice for the most precise of movements. The ones which can prove critical in an RTS or FPS game. It is also easy to use on a range of surfaces.

Logitech Flow technology is great to have access to, especially if you’re a streamer. You can play a game live for an audience, while you also monitor and moderate the stream chat on a second computer screen. You can move your mouse across as many as three different devices, so you can have the full gaming experience.

The premium ergonomic design of the MX vertical makes it look and feel like a mouse you want to use. The 57 degree angle, textured spiral-like grip, and large thumb rest make it a pleasure to use and provide fantastic protection for your wrist.

#2 Designed for gaming

ZLOT Vertical Gaming Mouse

ZLOT Vertical Gaming Mouse

Our Score: 4.75 / 5

Editor's opinion:

The ZLOT vertical gaming mouse is a cheap, dedicated gaming mouse with everything you need to play at your best.

The adjustable DPI goes as high as 3200, which gives you the ability to make the precise movements required in an FPS, or a smooth experience playing an RPG or MMO.

With six buttons, you can map all the in-game functions you need to it, which is especially useful for certain game genres.

Pros

  • Adjustable DPI which caps out at 3200
  • 6 buttons which can be mapped to in-game functions
  • Affordable dedicated gaming mouse
  • Ergonomic design minimises wrist pain while gaming

Cons

  • The joystick on the mouse isn’t great

The ZLOT gaming mouse is an interesting combination as both a vertical mouse and a dedicated gaming mouse. While it doesn’t execute it perfectly, for the price, you really can’t be too disappointed with this model. It has a lot of features that make the experience of gaming enjoyable, and even allows for high-level performance.

The adjustable DPI of this mouse gives you the flexibility to play all kinds of games, spanning all genres. The important part though is that it can go as high as 3200. This is good enough to rival mice that are much more expensive, and can give you a slight edge on the battlefield, especially if you enjoy playing FPS games.

With six different buttons, you’ll be able to customize this mouse and map your most-used functions onto it for ease of use. This feature is especially important if your genre of choice is RPGs or RTS, since these games often have abilities, and the easier it is to access them, the better your performance. There’s also a joystick, which can be useful in some cases, but generally isn’t the best according to a number of users on Amazon.

Last but not least is the smooth grip and ergonomic design of the ZLOT gaming mouse. This will ensure that however hard you game, your wrist will be sufficiently protected. The natural handshake position it encourages your arm to rest in will feel very comfortable if you spend some time getting used to it.

#3 Best lightweight mouse

Anker 2.4G Vertical Mouse

Anker 2.4G Vertical Mouse

Our Score: 4.75 / 5

Editor's opinion:

The Anker 2.4G is an affordable option, which still provides enough features to be worthy of gaming.

The adjustable optical DPI goes up to 1600, which makes this a great mouse to use for casual gaming.

After 8 minutes of being ideal, the Anker 2.4G will automatically shut off, and save your battery life if you stop gaming for a brief period.

Pros

  • Lightweight design makes it easy to move around
  • Battery saving kicks in after 8 minutes of inactivity
  • Affordable option
  • Adjustable DPI and solid tracking

Cons

  • Clicks can be stubborn, especially with the scroll wheel

The Anker 2.4G is the lightest mouse on this list, weighing just 3.36 ounces. The weight of a mouse can play a big role as far as gaming goes. The last thing you want while you’re about to rotate the camera is to find that your mouse is too heavy to make the movement quick enough. While this won’t make a huge difference to the casual gamer, having a light mouse can make all the difference to high-level gaming.

One of the neat features of this mouse is its battery saving mode. After eight minutes of inactivity, it will automatically shut down to save you some battery. This is useful for a wireless mouse, given that you don’t want it to die on you during the middle of a game. If you’re playing but you have to take a long phone call or break for food, you won’t have to worry about the battery life of your mouse draining the whole time.

Users tend to enjoy the tracking of this mouse, as well as the adjustable DPI settings. You’ll be able to use this mouse wherever you are, which is convenient if you like to game on the go. The adjustable DPI gives you the flexibility to change the sensitivity of the mouse depending on the style of game you are currently playing, so that you can make the most of it.

#4 Customizable Thumb Buttons

J-Tech Digital V628

J-Tech Digital V628

Our Score: 4.75 / 5

Editor's opinion:

The J-Tech Digital V628 is an attractive ergonomic mouse that can be used for more than just navigating web pages.

The removable palm rest gives your wrist extra support which makes it an excellent choice if you struggle with discomfort while gaming.

Customizable thumb buttons and the blue LED light are nice additional features that can enhance the overall gaming experience.

Pros

  • Adjustable DPI
  • Removable palm rest for added comfort
  • Customizable thumb buttons makes gaming easier
  • Cool blue LED light for evening gaming

Cons

  • The buttons are quite sensitive, making them easy to press by accident

The J-Tech V628 is a very competent mouse, and one which has everything you need for gaming.

The ergonomic design of the V628 makes it extremely satisfying to use, and comfortable for hours of gaming. The removable palm rest is a useful accessory to have, and it gives you flexibility in how you use the mouse. Those who suffer with RSIs will be the first to mention how comforting it is to have a place to lay the palm on a mouse.

Then there’s the customizable thumb buttons. This is the feature where this mouth excels and also falls a little short. When all is well, you’ll find the convenience of these buttons very rewarding for gaming. However, due to how sensitive they can be, you might find that you press them even when you don’t want to. This could potentially cause issues, especially if you game at a high level.

Other features which make the V628 a solid choice for gaming are the blue LED light, and the adjustable DPI. The blue light is very much a luxury rather than anything else, but it can help set the scene for a session of gaming late at night. The adjustable DPI is more practical, and can help you level up your precision to improve in FPS or RTS style games.

#5 Best for big hands

AUTLEY Vertical Mouse

AUTLEY Vertical Mouse

Our Score: 4.75 / 5

Editor's opinion:

The AUTLEY vertical mouse is an affordable vertical mouse with a robust design and silent clicking.

The large build lends itself well to anyone with big hands, plus it allows for a firm grip.

It also comes with adjustable DPI which maxes out at an impressive 3200, perfect for nailing precision movements.

Pros

  • Ideal for big hands
  • Silent clicking
  • Affordable option
  • Adjustable DPI up to 3200

Cons

  • Not suitable for small hands

The AUTLEY vertical mouse provides an excellent solution to those with large hands that struggle to find a comfortable mouse. Oftentimes mice will fit smaller hands perfectly, but leave those with big hands gripping them tight. This can lead to problems due to strain on the wrist and arm, so it’s best to seek out mice that are well suited to the size of your hand. If it happens to be big, then you’re in luck, as this mouse is a fantastic ergonomic model for gaming.

Pressing the buttons of the AUTLEY vertical mouse is pleasant, and the clicking sound is minimal. This makes it perfect for late-night gaming sessions without disturbing anyone who might be in the vicinity. It also just feels great, and the buttons are all well-placed for easy access.

For an affordable option, this mouse has incredible adjustable DPI. Not many in the same price range can boast a max of 3200 DPI. This will help you to victory in games where precise movements are key. This perhaps makes it one of the best ergonomic mice for gaming if you have big hands. Rare few mice offer a superior gaming experience and cater for big hands, it’s usually either one or the other.

The best ergonomic gaming mouse: buying guide, tips & tricks

There is a difference between a mouse suited for gaming and a regular mouse.

While many ergonomic mice haven’t been specifically designed to play games with, they can certainly hold their own. They also encourage a natural arm and wrist position, so you don’t have to worry as much about an injury that could potentially prevent you from gaming as much.

Important factors for mice suitable for gaming are as follows.

DPI

One of the top factors you’re likely to see in any debate about gaming mice is the DPI.

DPI (Dots Per Inch) refers to how quickly you’ll be able to move the cursor or crosshair across the screen. This is essential for pulling off those quick movements you need to master an FPS game, or saving a unit before it’s too late in an RTS. While it’s not everything, you should definitely consider the DPI of the mouse, especially so if you pride yourself on playing well every time you game.

Type of Sensor

The sensor at the base of a mouse is what determines how easily your movements are translated onto the screen, and how well the mouse will work on different surfaces.

There are two different types, each with their own pros and cons for gaming.

1. Laser sensor

The laser sensor will offer you a greater DPI rate, and allows you to use the mouse on a wide variety of surfaces. This makes it versatile, and solid for games where micro-movements are necessary.
As a result, you could argue it is greater for FPS and RTS games. The MX Vertical is a great example of a mouse with a laser sensor.

The downside to this type of sensor is that sometimes you can experience issues with lag, and jittery movement on the screen.

2. Optical sensor

The optical laser requires the use of a mouse pad to work well, but boasts greater accuracy and tracking. It’s also generally much more affordable, as seen with the Anker ergonomic mouse. For casual gaming, or a smoother experience, then you might enjoy this option over a laser sensor mouse.

The downside to optical sensors is the requirement of a mouse pad, which restricts you from using your mouse wherever you are, as well as the lower DPI.

Weight

The weight of the mouse isn’t super important for gaming performance, however, it can certainly play a part.

A heavier mouse, like the J-Tech V628 will feel more stable and better for games that require less precise movements like MMOs. On the other hand, light mouses like the Anker 2.4G can make you quicker which is essential for fast-paced games like FPS.

Buttons

For certain games, like RPG and RTS, you’ll need buttons that you can map to in-game functions. If you don’t have enough buttons on the mouse, you might lack the same streamlined gaming experience in those types of games as you otherwise would.

You also want to be sure that the buttons are conveniently placed, and easy to press. Some mice, like the V628 from J-Tech, provide handy thumb buttons that are easy to press in an instant.

Others, like the ZLOT gaming mouse, offer as many as six different buttons, which makes it an excellent choice for RTS and RPG games for example.

Final verdict

There are plenty of options if you’re looking for an ergonomic mouse that’s suitable for gaming. Not all of them will be perfect for your preferred genre or playstyle, but you should be able to find at least one that suits your needs.

Whether it’s high DPS and quick movements you’re after, or many customizable buttons for more in-game functionality, there’s something for you.

We highlighted the MX Vertical by Logitech and the ZLOT gaming mouse as the best overall in this category. The MX Vertical is an all-round stellar mouse, with all the functionality and performance you’d expect of a dedicated gaming mouse.

The high DPI and access to Logitech Flow technology should make it a strong contender for streamers and competitive gamers. The ZLOT device is a fantastic yet affordable gaming mouse. It offers an impressive 3200 DPI and ergonomic features which make it excellent for comfortable gaming. This is a great ergonomic mouse for both the casual and the experienced gamer on a budget.

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Samuel Dixon
Samuel Dixon

Sam is a freelance writer based in Spain, creating content and working on his blog in his spare time. He loves finding researching fitness-related products that introduce new ways of working out, currently practicing yoga and calisthenics as a way of staying healthy, but always experimenting with different forms of training.

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